Catheter -integrated soft multilayer electronic arrays for multiplexed sensing and actuation during cardiac surgery

Multimodal multiplexed soft sensors and actuators for minimally invasive surgery

WHAT IS KNOWN?

  1. Catheters are widely used for minimally invasive therapies such as atrial fibrillation ablation, intravascular stents, etc. In addition, they are also used for capturing information during procedures such as measuring temperature, pressure, electrograms etc.
  2. However, these catheters are limited by mechanical rigidity, low spatial densities, single function capability necessitating use of multiple catheters to acquire critical information.

WHAT THIS STUDY ADDS?

  1. We have designed a novel flexible, stretchable and tissue conforming electronics device integrated with a balloon catheter that supports simultaneous high-density spatiotemporal mapping of temperature, pressure, and electrograms.
  2. In addition, our device allows for programmable electrical stimulation, radio frequency ablation and irreversible electroporation.
  3. This novel device, the first of its kind, anywhere in the world, will eventually enable physicians to acquire a rich set of physiological information and complete surgeries and deliver therapies in shorter times than currently possible, with a single instrumented catheter system.

LINK TO THE ARTICLE

Mengdi Han*, Lin Chen*, Kedar Aras*, Cunman Liang, Xuexian Chen, Hangbo Zhao, Kan Li, Ndeye Rokhaya Faye, Bohan Sun, Jae-Hwan Kim, Wubin Bai, Quansan Yang, Yuhang Ma, Wei Lu, Enming Song, Janice Mihyun Baek, Yujin Lee, Clifford Liu, Jeffrey B. Model, Guanjun Yang, Roozbeh Ghaffari, Yonggang Huang, Igor R. Efimov, John A. Rogers. Catheter-integrated soft multilayer electronic arrays for multiplexed sensing and actuation during cardiac surgery. Nature Biomedical Engineering (2020). https://doi.org/10.1038/s41551-020-00604-w.